Development of a novel transplantation system using iPS-derived pancreatic islets
Atsushi Miyajima
Institute for Quantitative Biosciences
Professor
In order to use iPS-derived islets for clinical applications, we have been working on efficient generation of islets from iPS cells, scaling islet production and developing a method for encapsulation of islets to protect them from the recipient immune system. We have also developed a novel primate diabetic model to evaluate the functions of iPS-derived islets.
IQB University of Tokyo
Credit: IQB University of Tokyo
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Research collaborators
- Prof. Sakai, Takeuchi, Okitsu (Institute of Industrial Science)
- Prof. Michiue (Graduate School of Arts and Science)
- Drs. Shimoda and Okouchi (National Center for Global Medicine)
- Dr. Sasaki (Central Institute for Experimental Animals)
- Dr. Nakaishi (Kaneka Corp)
- Prof. Michiue (Graduate School of Arts and Science)
- Drs. Shimoda and Okouchi (National Center for Global Medicine)
- Dr. Sasaki (Central Institute for Experimental Animals)
- Dr. Nakaishi (Kaneka Corp)
Related publications
- Metre-long cell-laden microfibres exhibit tissue morphologies and functions. Nature Materials 2013 Jun;12(6):584-90
Related patents
- Method to make islets from multipotential stem cells:PCT/JP2014/054352
Contact
- Tel: +81-3-5841-7884
- Email: miyajima[at]iam.u-tokyo.ac.jp
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