Brain Information Dynamics (Grants-in-Aid for Scientific Research on Innovative Areas)

1.2 Data science
1.3 Artificial intelligence fundamentals
1.4 Cognitive science
1.5 Neuroscience
3.5 Biology
3.7 Medicine, dentistry and pharmacy
3.8 Informatics

Haruhiko Bito

Graduate School of Medicine

Professor

The goal is to establish a new cross-disciplinary research field, "Brain Information Dynamics". This encompasses the construction and modeling of local cytoarchitecture, which is able to define information flow in the brain, high-resolution recording and manipulation of multi-area network dynamics, model validation with a view to closed-loop control, and the construction of innovative brain-based architectures that incorporate the results of these studies.

Elucidation for the establishment of brain information dynamics
Brain Information Dynamics (Grants-in-Aid for Scientific Research on Innovative Areas)

Related publications

Inoue et al., Cell 177, 1346-1360 (2019); Tanaka et al., Nat Human Behavior 1, 748-756 (2017), Hoang et al., Front Comput Biol 16, e1008075 (2020); Yamakawa, Front Comput Neurosci 14, 74 (2020), Yamazaki T et al. Human-scale Brain Simulation via Supercomputer: A Case Study on the Cerebellum. Neuroscience. 462: 235-246 (2021).

Related patents

1.US patent 10836802 (US20170152295, 2020.11.17), Canadian Patent CA2951780 (2020.2.11), European Patent EP 3156482 (2017.4.19), Chinese Patent CN106687588 (2017.5.17), India Patent IN201617042532 (2017.3.24)
Inventors: Haruhiko Bito, Masatoshi Inoue, Atsuya Takeuchi, Junichi Nakai, Masamichi Okura;
Invention: Calcium reporter gene,
Assignee: Japan Science and Technology Agency

2.出願番号PCT/JP2013/068289, 特願2012-205892
発明者：尾藤晴彦、奥野浩行、川島尚之
発明の名称「神経活動依存的プロモータ活性を有するDNA、及びこれを含むベクター」　(特許第5971661号【登録日】2016年7月22日)
出願人：東京大学